While wireless endoscopic capsule examining human’s large gastrointestinal (GI) cavity, such as stomach and large intestine, it is possible that many interested spots are omitted by the one or two cameras due to its limited field of view. This paper proposes a new globularity capsule endoscopy system with multi-camera. Through analyzing the multi-camera system’s optical characteristic and power consumption of the endoscopic capsule system, this paper proposes the spatial physical structure and the electronic architecture of the globularity capsule without blind area. Its diameter can be less than 15mm. The capsule can work in human’s GI tract for 8 hours when the image frame rate is 4fps.